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Genetic and Rare Diseases Information Center (GARD)

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Sertoli-leydig cell tumors


Other Names for this Disease

  • Androblastoma of ovary
  • Arrhenoblastoma
  • Arrhenoblastoma of ovary
  • Sertoli-leydig cell tumor of the ovary
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Overview

Sertoli-Leydig cell tumors are a cancer that starts in the female ovaries. The cancer cells produce and release a male sex hormone which may cause the development of male physical characteristics (virilization), including facial hair and a deep voice.[1] This type of tumor is sometimes called arrhenoblastoma of the ovary or a stromal tumor.[1][2] Sertoli-Leydig cell tumors are rare tumors which account for less than 0.5% of all ovarian tumors. While they can be found in women of all age groups, they are most common in young women. Treatment involves surgery and chemotherapy or radiation if the cancer has spread. Because Sertoli-Leydig cell tumors have a low chance of spreading, if the tumor is found early, chances for survival are good.[2]
Last updated: 3/25/2010

References

  1. Dugdale DC, Mason JR. Sertoli-Leydig cell tumor. MedlinePlus. 2008; http://www.nlm.nih.gov/medlineplus/ency/article/001172.htm. Accessed 3/25/2010.
  2. Vorvick LJ, Chen YB. Arrhenoblastoma of ovary. MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/ency/article/001507.htm. Accessed 3/25/2010.
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Other Names for this Disease
  • Androblastoma of ovary
  • Arrhenoblastoma
  • Arrhenoblastoma of ovary
  • Sertoli-leydig cell tumor of the ovary
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.