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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Lynch syndrome


Other Names for this Disease

  • COCA1
  • Colon cancer, familial nonpolyposis
  • Colorectal cancer, hereditary nonpolyposis
  • Familial nonpolyposis colon cancer
  • Hereditary nonpolyposis colorectal cancer
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Management Guidelines

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Lynch syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
  • Lynch Syndrome International (LSI) Web site lists Lynch syndrome clinical trials and patient registries. Click on the link above to view the list.
  • Orphanet lists clinical trials, research studies, and patient registries enrolling people with this condition. Click on Orphanet to view the list.

Medical Products

The medication(s) listed in the table(s) below have been approved by the Food and Drug Administration (FDA) for treatment of this condition. The FDA Office of Orphan Products Development designates "orphan products" for those that treat rare diseases affecting fewer than 200,000 Americans. The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products. To search for all FDA approved drugs, visit Drugs@FDA. You can find orphan products used to treat other conditions by searching the Orphan Drug Product Designation database.


Generic Name Leucovorin
Trade Name
(Manufacturer Name)
Leucovorin calcium®
(Bedford Laboratories)
Indication
The FDA has approved this product to be used in this manner.
For use in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer.
More Information about this product Drug Information Portal
Medline Plus Health Information

Other Names for this Disease
  • COCA1
  • Colon cancer, familial nonpolyposis
  • Colorectal cancer, hereditary nonpolyposis
  • Familial nonpolyposis colon cancer
  • Hereditary nonpolyposis colorectal cancer
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.