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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Pityriasis lichenoides et varioliformis acuta


Other Names for this Disease
  • Mucha-Habermann disease
  • PLEVA
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Treatment


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How might pityriasis lichenoides et varioliformis acuta (PLEVA) be treated?

Many treatments have been reported for PLEVA, although their effectiveness varies among people with this condition. Depending on the severity of PLEVA, treatment may include increased sun exposure, topical steroids, topical immunomodulators (such as tacrolimus or pimecrolimus), oral antibiotics (such as erythromycin or tetracycline), phototherapy, systemic steroidsmethotrexate, acitretin, dapsone, ciclosporin, or etanercept. PLEVA may not always respond to treatment and relapses often occur when treatment is discontinued.[1][2]
Last updated: 5/2/2012

References
  1. Pityriasis lichenoides. New Zealand Dermatological Society Web site. 2011; http://dermnetnz.org/scaly/pityriasis-lichenoides.html. Accessed 1/3/2012.
  2. Nikkels AF, Gillard P, Piérard GE. Etanercept in therapy multiresistant overlapping pityriasis lichenoides. J Drugs Dermatol. 2008 Oct;7(10):990-2. http://www.ncbi.nlm.nih.gov/pubmed/19112768 .


Clinical Trials & Research for this Disease

  • The U.S. National Institutes of Health, through the National Library of Medicine, developed ClinicalTrials.gov to provide patients, family members, and members of the public with current information on clinical research studies. There is a study titled Evaluation and Treatment of Patients with Dermatologic Diseases which may be of interest to you. To find this trial, click on the link above.
  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. There is a study titled Dermatology Consultation Clinic and Clinical Research that may be of interest to you. You may want to contact the investigator, Maria Turner (maria.turner@nih.gov) to learn more.