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Other Names for this Disease
- Hereditary white nails
- Nail disorder, nonsyndromic congenital, 3
- Porcelain nails
- Total leukonychia
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 It is usually inherited in an autosomal dominant manner. Less commonly, it may be inherited in an autosomal recessive manner, or acquired (not inherited) during a person's lifetime. The inherited forms can be caused by mutations in the PLCD1 gene and generally involve the entire plate of all 20 nails. In some cases, leukonychia totalis has been associated with various other abnormalities or syndromes. Treatment may focus on the underlying cause when it is associated with another condition.Leukonychia totalis is a nail condition characterized by complete whitening of the entire nail plate.
Last updated: 2/18/2014
- Howard SR, Siegfried EC. A case of leukonychia. J Pediatr. September, 2013; 163(3):914-915. Accessed 2/18/2014.
- Yalçin Tüzün, Özge Karakus. Leukonychia. J Turk Acad Dermatol. 2009; 3(1):Accessed 2/18/2014.
- Marla J. F. O'Neill. NAIL DISORDER, NONSYNDROMIC CONGENITAL, 3; NDNC3. OMIM. August 11, 2011; http://omim.org/entry/151600. Accessed 2/18/2014.
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In Depth Information
- The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Leukonychia totalis. Click on the link to go to OMIM and review these resources.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Leukonychia totalis. Click on the link to view a sample search on this topic.