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Thrombocytopenia, acquired amegakaryocytic


Other Names for this Disease

  • AAT
  • Acquired pure megakaryocytic aplasia
  • Severe thrombocytopenia and selective, marked decrease or absence of megakaryocytes
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Overview

Acquired amegakaryocytic thrombocytopenia is characterized by severe thrombocytopenia (lack of platelets) with no other blood abnormalities.[1] It is so named because the level of the large bone marrow cells that produce platelets, called megakaryocytes, are significantly lower or absent. The course of the condition is variable, but the condition can become life-threatening. Its cause is currently unknown.[1]
Last updated: 6/10/2009

References

  1. Bulcahndani D et al.,. Acquired pure megakaryocytic aplasia: Report of a single case treated with Mycophenolate Mofetil. American Journal of Hematology. 2007;
  2. Felderbauer P et al.,. Case Report: Acquired pure megakaryocytic aplasia: a seoarate haematological disease entity or a syndrome with multiple causes?. Eur J Haematol. 2004;
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Basic Information

  • MedlinePlus provides┬álists many resources and provides more information on blood disorders in general that you may find helpful. MedlinePlus is a Web site designed by the National Library of Medicine to help you research your health questions.
  • The National Heart Lung and Blood Institute (NHLBI) provides information on thrombocytopenia in general. The NHLBI was created to conduct research and distribute health information on diseases of the heart, blood vessels, lungs, and blood.

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Other Names for this Disease
  • AAT
  • Acquired pure megakaryocytic aplasia
  • Severe thrombocytopenia and selective, marked decrease or absence of megakaryocytes
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.