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Genetic and Rare Diseases Information Center (GARD)

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Linear porokeratosis

Other Names for this Disease
  • Congenital facial linear porokeratosis (type)
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How might linear porokeratosis be treated?

Because linear porokeratosis is a rare condition, there is no established treatment protocol.  Protection from sun exposure and regular visits to a doctor to check for skin cancer are encouraged as routine care.  Treatment options depend on the size, location, and severity of the characteristic skin markings.  Several medications (5-fluorouracil, acitretin) have been shown to be effective for treating this condition in a small number of patients.[1]  We identified a single report of photodynamic therapy being used to successfully treat an individual with linear porokeratosis.[2]  Surgery is recommended to remove any skin cancer that may develop.[1]
Last updated: 11/17/2011

  1. Spencer LV . Porokeratosis. Medscape Reference. May 30, 2012; Accessed 8/21/2012.
  2. García-Navarro X, Garcés JR, Baselga E, Alomar A. Linear porokeratosis: excellent response to photodynamic therapy. Archives of Dermatology. 2009; 145:526-527. Accessed 11/15/2011.