Other Names for this Disease
- Fatal pneumococcal Waterhouse-Friderichsen syndrome
Your QuestionMy sister recently passed away from Waterhouse–Friderichsen syndrome. Can you help me find information about this condition?
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Questions on this page
Waterhouse-Friderichsen syndrome is characterized by the abrupt onset of fever, petechiae, septic shock, and disseminated intravascular coagulation (DIC) followed by acute hemorrhagic necrosis of the adrenal glands and severe cardiovascular dysfunction. Patients often experience prodromic, nonspecific symptoms, including malaise, headache, weakness, dizziness, cough, arthralgia (joint pain), and myalgia (muscle pain).
A characteristic skin rash with a typical evolution occurs in approximately 75% of patients with Waterhouse-Friderichsen syndrome.
- Vorvick L, Vyas JM. Waterhouse-Friderichsen syndrome. MedlinePlus. 2009; http://www.nlm.nih.gov/medlineplus/ency/article/000609.htm. Accessed 1/8/2010.
- Tritos NA. Adrenal Hemorrhage. eMedicine. 2008; http://emedicine.medscape.com/article/126806-overview.
- Spence RK, Long JC, Lasker JC. Hemostatic Disorders, Nonplatelet. eMedicine. 2006; http://emedicine.medscape.com/article/210467-overview.
- de Assis Aquino Gondim F, Singh MK, Croul SE. Meningococcal Meningitis. eMedicine. 2009; http://emedicine.medscape.com/article/1165557-overview. Accessed 1/8/2010.