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Genetic and Rare Diseases Information Center (GARD)

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Brenner tumor of ovary

Other Names for this Disease
  • Ovarian Brenner tumor
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Tests & Diagnosis

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How is a Brenner tumor of the ovary diagnosed?

Approximately 90% of Brenner tumors of the ovary are discovered by chance during a gynecologic operation.[1] They often occur at the same time as other ovarian tumors or cancers.[2][3]  Most benign Brenner tumors make a protein called p63.  Because other ovarian tumors and malignant Brenner tumors do not make this protein, p63 is considered a tumor marker for Brenner tumors of the ovary.  Therefore, if p63 is identified in a patient, this may help to diagnose a Brenner tumor of the ovary.[3]
Last updated: 1/11/2012

  1. Katz VL, Lentz GM, Lobo RA, Gershenson DM. Comprehensive Gynecology, 5th edition. Philadelphia, PA: Mosby Elsevier; 2007;
  2. Curran D. Benign Lesions of the Ovaries. eMedicine. 2011; Accessed 1/11/2012.
  3. Stany MP, Hamilton CA. Obstet Gynecol Clin North Am. 2008; 35:271-284. Accessed 1/11/2011.