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Genetic and Rare Diseases Information Center (GARD)

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Pineoblastoma is a cancerous (malignant) tumor that develops in the pineal gland.  The pineal gland is located in the brain and makes the hormone melatonin to regulate the body's sleep patterns.  Pineoblastoma is a type of primitive neuroectodermal tumor (PNET).  Pineoblastoma mainly affects children, but can also occur in adults.[1]  Treatment of pineoblastoma includes surgery to remove as much of the tumor as possible, followed by radiation therapy and chemotherapy.[2]
Last updated: 12/15/2011


  1. Li MH, Bouffet E, Hawkins CE, Squire JA, Huang A. Molecular genetics of supratentorial primitive neuroectodermal tumors and pineoblastoma. Neurosurgical Focus. 2005; 19:E3. Accessed 12/12/2011.
  2. Tate MC, Rutkowski MJ, Parsa AT. Contemporary management of pineoblastoma. Neurosurgery Clinics of North America. 2011; 22:409-412. Accessed 12/12/2011.
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