Other Names for this Disease
- Nodose hair
What causes monilethrix?
Is genetic testing for monilethrix clinically available?
What are the characteristics of monilethrix?
What parts of the body does monilethrix affect?
How do people inherit monilethrix?
Is there treatment available for monilethrix? Is there a cure for the condition?
While there is no recognized definitive treatment for monilethrix, oral acitretin and topical 2% minoxidil have shown good clinical and cosmetic results with continued use. The systemic administration of vitamins, retinoids, griseofulvin, oral contraceptives, steroids, radiation therapy, external desquamative ointments, and steroid preparations have not show impressive results.
Avoiding trauma is perhaps the most effective method of managing monilethrix. This is because from birth, the hair of individuals with monilethrix tends to have an increased susceptibility to weathering and cosmetic damage (e.g., sunlight exposure, dyeing, bleaching, perming, curling). This susceptibility to damage can prevent hair from growing to its maximum length.
- Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Chapter 661 - Disorders of Hair. Kliegman: Nelson Textbook of Pediatrics, 18th ed. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2007;
- Schwartz RA, Alexiewicx-Slowinska M. Monilethrix. Medscape Reference. May 13, 2011; http://emedicine.medscape.com/article/1118500-overview#. Accessed 1/30/2012.
- Monilethrix. Online Mendelian Inheritance in Man (OMIM). May 6, 2010; http://omim.org/entry/158000. Accessed 1/30/2012.
- Farooq M, Ito M, Naito M, Shimomura Y. A case of monilethrix caused by novel compound heterozygous mutations in the desmoglein 4 (DSG4) gene. Br J Dermatol. 2011; http://www.ncbi.nlm.nih.gov/pubmed/21495994. Accessed 1/30/2012.
- Karincaoglu Y, Coskun BK, Seyhan ME, Bayram N. Monilethrix: improvement with acitretin. Am J Clin Dermatol. 2005; http://www.ncbi.nlm.nih.gov/pubmed?term=16343029. Accessed 1/31/2012.
- Rossi A, Iorio A, Scali E, Fortuna MC, Mari E, Palese E, Greco P, Carlesimo M. Monilethrix treated with minoxidil. Int J Immunopathol Pharmacol. 2011; http://www.ncbi.nlm.nih.gov/pubmed?term=21496408. Accessed 1/31/2012.