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Genetic and Rare Diseases Information Center (GARD)

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Acute disseminated encephalomyelitis


Other Names for this Disease

  • ADE
  • ADEM
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Overview

Acute disseminated encephalomyelitis (ADEM) is a neurological condition characterized by a brief but intense attack of inflammation in the brain and spinal cord that damages myelin – the protective covering of nerve fibers.  It often follows viral infection, or less often, vaccination for measles, mumps, or rubella. Treatment for ADEM is targeted at suppressing inflammation in the brain using anti-inflammatory drugs. Plasmapheresis or intravenous immunoglobulin therapy may also be used.  Additional treatment is symptomatic and supportive.[1] 
Last updated: 10/31/2011

References

  1. NINDS Acute Disseminated Encephalomyelitis Information Page. National Institute of Neurological Disorders (NINDS). November 2010; http://www.ninds.nih.gov/disorders/acute_encephalomyelitis/acute_encephalomyelitis.htm. Accessed 7/27/2011.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Acute disseminated encephalomyelitis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • ADE
  • ADEM
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.