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Genetic and Rare Diseases Information Center (GARD)

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Berger disease


Other Names for this Disease

  • Berger's disease
  • Glomerulonephritis, IGA
  • IGA nephropathy
  • IGAN
  • Nephritis, IGA type
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Overview

Berger disease (frequently called IgA nephropathy) is a kidney disorder that occurs when IgA, a protein that helps the body fight infections, settles in the kidneys. The cause of this condition is unknown. After many years, deposits of IgA may cause the kidneys to leak blood and sometimes protein in the urine. In the early stages, Berger disease has no symptoms. The first sign of this condition may be blood in the urine. After 10 to 20 years with Berger disease, the kidneys may show signs of damage. Treatment focuses on slowing the disease and preventing complications.[1]

Berger disease can occur at any age, even in childhood. About 25 percent of adults and 5 to 10 percent of children with Berger disease develop total kidney failure. Total kidney failure means the kidney damage is permanent and dialysis or a kidney transplant is required.[1] 
Last updated: 8/17/2009

References

  1. IgA Nephropathy. National Kidney and Urologic Diseases Information Clearinghouse. February 2008; http://www.kidney.niddk.nih.gov/kudiseases/pubs/iganephropathy/. Accessed 8/17/2009.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Berger disease. We will answer your question and update these pages with new resources and information.

Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), conducts and supports research on a broad spectrum of diseases affecting public health. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Berger disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Berger's disease
  • Glomerulonephritis, IGA
  • IGA nephropathy
  • IGAN
  • Nephritis, IGA type
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.