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Other Names for this Disease
- Agressive systemic mastocytosis
- Indolent systemic mastocytosis
- Mast cell leukemia
- Systemic mast cell disease
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Treatment for systemic mastocytosis is based on each individual's symptoms. This includes efforts to control anaphylaxis and other allergic reactions, itching (pruritus) and flushing, and intestinal malabsorption. Some of the medications used to treat systemic mastocytosis include:
Antihistamines to treat itching, other skin complaints, severe flushing and low blood pressure before symptoms appear, and ulcers;
Proton pump inhibitors to relieve ulcer-like symptoms;
Epinephrine to treat symptom flares which occur with shock, referred to as anaphylaxis;
- Steroids to treat malabsorption (impaired ability to take in nutrients); and
- Cromolyn sodium which may help reduce cramping in the abdomen.
Last updated: 10/5/2012
- Krishnan K, Jaishankar D. Systemic Mastocytosis Treatment & Management. Medscape Reference. February 2012; http://emedicine.medscape.com/article/203948-treatment#showall. Accessed 10/5/2012.
- Mastocytosis: Treatment. National Institute of Allergy and Infectious Diseases (NIAID). January 2011; http://www.niaid.nih.gov/topics/mastocytosis/Pages/Treatment.aspx. Accessed 10/5/2012.
Clinical Trials & Research for this Disease
- ClinicalTrials.gov lists trials that are studying or have studied Systemic mastocytosis. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.