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Genetic and Rare Diseases Information Center (GARD)

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Acanthosis nigricans


Other Names for this Disease

  • AN
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Acanthosis nigricans is a skin disorder in which there is darker, thick, velvety skin in body folds and creases. This condition usually appears slowly and doesn't cause any symptoms other than skin changes. Eventually, dark, velvety skin with very visible markings and creases appears in the armpits, groin and neck folds, and over the joints of the fingers and toes. Less commonly, the lips, palms, soles of the feet, or other areas may be affected. These symptoms are more common in people with cancer. The exact cause of this condition is not well understood; but it can be genetically inherited or related to medical problems such as obesity, some prescription drugs, and cancer.[1]
Last updated: 7/25/2011

References

  1. Acanthosis nigricans. MedlinePlus. September 2010; http://www.nlm.nih.gov/medlineplus/ency/article/000852.htm. Accessed 7/25/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Acanthosis nigricans. We will answer your question and update these pages with new resources and information.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Acanthosis nigricans. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • AN
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.