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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Panuveitis


Other Names for this Disease

  • Inflammation of the whole uveal tract
  • Total uveitis
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Treatment

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How might panuveitis be treated?

Panuveitis may be treated in several ways, including injections around the eye, oral medications, and eye drops.[1][2] Corticosteroids are the treatment of choice for most types of uveitis, including panuveitis. For panuveitis, both topical and systemic corticosteroids are needed. Depending on the severity of the disease, oral prednisolone is typically started in a larger dose, and then is tapered off a few weeks after starting therapy as inflammation improves. A maintenance dose is typically used thereafter. Immunomodulating drugs (which alter the body's immune response) are needed if the inflammation cannot be controlled with corticosteroids. Cycloplegics (eye drops that temporarily paralyze the ciliary body) are used to help with pain due to ciliary spasms.[2]

Forms of uveitis due to infectious agents are treated by specific antimicrobial therapy (antibiotics, antiparasitics or antivirals), with or without corticosteroids.[2]
Last updated: 7/23/2014

References
  1. Facts About Uveitis. National Eye Institute. August, 2011; http://www.nei.nih.gov/health/uveitis/uveitis.asp. Accessed 7/22/2014.
  2. Reema Bansal, Vishali Gupta, and Amod Gupta. Current approach in the diagnosis and management of panuveitis. Indian Journal of Ophthalmology. Jan-Feb, 2010; 58(1):45-54. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841373/. Accessed 7/22/2014.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Panuveitis. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.

Medical Products

The medication(s) listed in the table(s) below have been approved by the Food and Drug Administration (FDA) for treatment of this condition. The FDA Office of Orphan Products Development designates "orphan products" for those that treat rare diseases affecting fewer than 200,000 Americans. The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products. To search for all FDA approved drugs, visit Drugs@FDA. You can find orphan products used to treat other conditions by searching the Orphan Drug Product Designation database.


Generic Name Dexamethasone Intravitreal Implant
Trade Name
(Manufacturer Name)
Ozurdex
(Allergan)
Indication
The FDA has approved this product to be used in this manner.
For treating non-infectious ocular inflammation, or uveitis, affecting eye's posterior segment
More Information about this product Drug Information Portal

Other Names for this Disease
  • Inflammation of the whole uveal tract
  • Total uveitis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.