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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Hashimoto's encephalitis


Other Names for this Disease
  • Hashimoto's encephalopathy
  • Steroid-responsive encephalopathy associated with autoimmune thyroiditis
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Overview


Hashimoto's encephalitis (HE) is a rare autoimmune disease with neurological and psychiatric features.[1][2][3][4] The condition is characterized by high titers of antithyroid antibodies in blood and cerebrospinal fluid (CSF).[1][2][4] Two types of HE have been suggested: a vasculitic type characterized by multiple relapsing-remitting stroke-like episodes and mild cognitive impairment, and a diffuse progressive type characterized by dementia and psychiatric symptoms.[1][3] Patients are mostly women.[1] Treatment includes steroids, plasmapheresis (plasma exchange), or immunosuppressant medications.[1][2][4]
Last updated: 4/16/2010

References

  1. Mijajlovic M, Mirkovic M, Dackovic, J et al.. J Neurol Sci. 2010; http://www.ncbi.nlm.nih.gov/pubmed/19846119. Accessed 4/16/2010.
  2. Mocellin R, Walterfang M, Velakoulis D. CNS Drugs. 2007; http://www.ncbi.nlm.nih.gov/pubmed/17850170. Accessed 4/16/2010.
  3. Marshall GA, Doyle JJ. J Neuropsychiatry Clin Neurosci. 2006; http://neuro.psychiatryonline.org/cgi/content/full/18/1/14. Accessed 4/16/2010.
  4. Schiess N, Pardo CA. Ann N Y Acad Sci. 2008; http://www.ncbi.nlm.nih.gov/pubmed/18990131. Accessed 4/16/2010.
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In Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hashimoto's encephalitis. Click on the link to view a sample search on this topic.

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