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Genetic and Rare Diseases Information Center (GARD)

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Moebius syndrome

Other Names for this Disease
  • Absence or underdevelopment of the 6th and 7th cranial nerves
  • Congenital facial diplegia
  • Congenital facial diplegia syndrome
  • Congenital oculofacial paralysis
  • MBS
More Names
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Is Moebius syndrome inherited?

Most cases of Moebius syndrome are not inherited and occur as isolated cases in individuals with no history of the condition in their family (sporadically). A small percentage of cases of Moebius syndrome have been familial (occurring in more than one individual in a family), but a there has not been a consistent pattern of inheritance among all affected families.[1][2] In some families the pattern has been suggestive of autosomal dominant inheritance, while in other families it has been suggestive of autosomal recessive or X-linked recessive inheritance.[2]
Last updated: 7/15/2013

  1. Moebius syndrome. Genetics Home Reference. July 2010; Accessed 7/15/2013.
  2. Marla J. F. O'Neill. MOEBIUS SYNDROME; MBS. OMIM. July 26, 2012; Accessed 7/15/2013.