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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Diabetic mastopathy


Other Names for this Disease
  • Diabetic fibrous breast disease
  • Diabetic fibrous mastopathy
  • Lymphocytic mastitis
  • Lymphocytic mastopathy
  • Sclerosing lymphocytic lobulitis
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Overview



What is diabetic mastopathy?


What causes diabetic mastopathy?


What is diabetic mastopathy?

Diabetic mastopathy are noncancerous lesions in the breast most commonly diagnosed in premenopausal women with type 1 diabetes.[1][2][3] The cause of this condition is unknown.[1][2][3][4][5] Symptoms may include hard, irregular, easily movable, discrete, painless breast mass(es).[1][4][6]
Last updated: 7/24/2013

What causes diabetic mastopathy?

The cause of diabetic mastopathy is unknown. Theories include an autoimmune reaction, genetic factors such as human leukocyte antigen (HLA) type, association with insulin therapy, and association with hyperglycemia.[1][2][5]
Last updated: 7/24/2013

References
  1. Keyoung JA Zuurbier CA, Tsangaris TN, Azumi N, Makariou E. Diabetic Mastopathy. Applied Radiology. 2003; http://www.medscape.com/viewarticle/462248_3. Accessed 10/15/2009.
  2. Honda M, Mori Y, Nishi T, Mizuguchi K, Ishibashi M. Diabetic mastopathy of bilateral breasts in an elderly Japanese woman with type 2 diabetes: a case report and a review of the literature in Japan. Intern Med. Epub 2007 Sep 14; https://www.jstage.jst.go.jp/article/internalmedicine/46/18/46_18_1573/_article. Accessed 10/15/2009.
  3. Sotome K, Ohnishi T, Miyoshi R, Nakamaru M, Furukawa A, Miyazaki H, Morozumi K, Tanaka Y, Iri H. An Uncommon Case of Diabetic Mastopathy in Type II Non-Insulin Dependent Diabetes Mellitus. Breast Cancer. 2006; https://www.jstage.jst.go.jp/article/jbcs/13/2/13_2_205/_article. Accessed 10/15/2009.
  4. Tsung JS, Wang TY, Lin CK. Diabetic mastopathy in type II diabetes mellitus. J Formos Med Assoc. 2005; http://www.ncbi.nlm.nih.gov/pubmed/?term=Tsung+JS%2C+Wang+TY%2C+Lin+CK. Accessed 10/15/2009.
  5. Ely KA, Tse G, Simpson JF, Clarfeld R, Page DL. Diabetic mastopathy: a clinicopathologic review. Am J Clin Pathol. 2000 Apr; http://ajcp.metapress.com/app/home/contribution.asp?referrer=parent&backto=issue,10,16;journal,96,99;linkingpublicationresults,1:300401,1. Accessed 10/15/2009.
  6. What you need to know about breast cancer. National Cancer Institute. 2005 ; http://www.cancer.gov/cancertopics/wyntk/breast/page1. Accessed 10/15/2009.