Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Omenn syndrome


Other Names for this Disease

  • Reticuloendotheliosis familial with eosinophilia
  • Severe combined immunodeficiency with hypereosinophilia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Symptoms

Newline Maker

What are the signs and symptoms of Omenn syndrome?

Infants with Omenn syndrome typically present shortly after birth, usually by 3 months of age. This is similar to other types of severe combined immunodeficiency (SCID). The characteristic skin findings (red and peeling skin), chronic diarrhea, and failure to thrive often precede the onset of infections. Life-threatening infections caused by common viral, bacterial, and fungal pathogens occur next. Lymphadenopathy and hepatosplenomegaly, both symptoms unique to Omenn syndrome, develop next.[1]
Last updated: 3/21/2012

References
  1. Schwartz RA, Lin RY. Omenn Syndrome. eMedicine. May 9, 2011; http://emedicine.medscape.com/article/887687-overview. Accessed 3/21/2012.


Other Names for this Disease
  • Reticuloendotheliosis familial with eosinophilia
  • Severe combined immunodeficiency with hypereosinophilia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.