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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Palmoplantar keratoderma


Other Names for this Disease
  • Keratoderma, Palmoplantar
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Treatment


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How might palmoplantar keratoderma be treated?

Treatment of both hereditary and nonhereditary palmoplantar keratodermas is difficult. Treatment usually only results in short-term improvement and often has adverse side effects.[1] The goal of treatment is usually to soften the thickened skin and makes it less noticeable.[2] Treatment may include simple measures such as saltwater soaks, emollients, and paring. More aggressive treatment includes topical keratolytics, topical retinoids, systemic retinoids (acitretin), topical vitamin D ointment (calcipotriol), or surgery to removed the skin, following by skin grafting.[1][2]
Last updated: 4/29/2011

References
  1. Lee RA & Elston DM. Keratosis Palmaris et Plantaris. eMedicine. July 2008; http://emedicine.medscape.com/article/1108406-overview#a1. Accessed 4/29/2011.
  2. Palmoplantar keratoderma. DermNet. June 2009; http://www.dermnet.org.nz/scaly/palmoplantar-keratoderma.html. Accessed 4/29/2011.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Palmoplantar keratoderma. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.