Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Megalocytic interstitial nephritis

Other Names for this Disease
  • Interstitial megalocytic nephritis
  • Transplant megalocytic interstitial nephritis (type)
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Megalocytic interstitial nephritis is a rare chronic kidney disease that is characterized by inflammation of the kidney. It is similar to malakoplakia of the kidney. In this condition the inflammation is caused by various infiltrate, particularly histiocytes. A histiocyte is a type of immune cell that eats foreign substances in an effort to protect the body from infection.
Last updated: 4/2/2009


  1. Tolkoff-Rubin NE, Rubin RH, Contran RS. Urinary Tract Infection, Pyelonephritis, and Reflux Nephropathy. In: Brenner BM, Levine SA. Brenner & Rector's THE KIDNEY 8th ed. Philadelphia, PA: 2008;
  2. Kapasi H, Roberstson S, Futter N. Diagnosis of renal malacoplakia by fine needle aspiration cytology. A case report. Acta Cytol. 1998 Nov-Dec;
  3. Krupp G et al. Tumefactive megalocytic interstitial nephritis in a patient with Escherichia coli bacteremia. Am J Kidney Dis. 1995 Jun;
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Megalocytic interstitial nephritis have been answered. See questions and answers. You can also submit a new question.

Basic Information

In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Megalocytic interstitial nephritis. Click on the link to view a sample search on this topic.