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Genetic and Rare Diseases Information Center (GARD)

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Vogt-Koyanagi-Harada syndrome

Other Names for this Disease
  • VKH syndrome
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What are the signs and symptoms of Vogt-Koyanagi-Harada syndrome?

Vogt-Koyanagi-Harada syndrome affects the eyes, ears, skin (cutaneous), and nervous system. Early symptoms include headache, dizziness, neck stiffness, vomiting, and low-grade fever. The symptoms progress to sudden visual loss in one or both eyes, eye pain, eye swelling and irritation (uveitis, choroiditis) and hearing disturbances.  Changes in the coloring of the skin and hair are usually observed three months after symptoms first appear and they are often permanent.[1] Vision and hearing generally improve with medical treatment. [2]
Last updated: 3/14/2014

  1. Choczaj-Kukula A.. Vogt-Koyanagi-Harada Syndrome. Emedicine. July 15, 2009; Accessed 10/28/2010.
  2. Fang W, Yang P.. Vogt-Koyanagi-Harada. Current Eye Research. May, 2008; Accessed 10/28/2010.