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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Tourette syndrome

*

* Not a rare disease

Other Names for this Disease

  • Gilles de la Tourette's syndrome
  • Tourette disorder
  • Tourette's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Inheritance

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Is Tourette syndrome inherited?

Evidence from twin and family studies suggests that Tourette syndrome is an inherited disorder. Although early family studies suggested an autosomal dominant mode of inheritance (an autosomal dominant disorder is one in which only one copy of the defective gene, inherited from one parent, is necessary to produce the disorder), more recent studies suggest that the pattern of inheritance is much more complex.  Although there may be a few genes with substantial effects, it is also possible that many genes with smaller effects and environmental factors may play a role in the development of Tourette syndrome. Genetic studies also suggest that some forms of ADHD and OCD are genetically related to Tourette syndrome, but there is less evidence for a genetic relationship between Tourette syndrome and other neurobehavioral problems that commonly co-occur with Tourette syndrome.[1]

Due to the complex nature of Tourette syndrome inheritance, affected families and those at risk may benefit from consulting with a genetics professional. Information about how to locate a genetics professional is provided in the Services section.  
Last updated: 4/21/2011

References
  1. Tourette Syndrome Fact Sheet. National Institute of Neurological Disorders and Stroke (NINDS). 2010 ; http://www.ninds.nih.gov/disorders/tourette/detail_tourette.htm. Accessed 2/24/2010.


Other Names for this Disease
  • Gilles de la Tourette's syndrome
  • Tourette disorder
  • Tourette's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.