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Genetic and Rare Diseases Information Center (GARD)

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Arthrogryposis multiplex congenita

Other Names for this Disease
  • Arthrogryposis
  • Congenital arthromyodysplasia
  • Congenital multiple arthrogryposis
  • Fibrous ankylosis of multiple joints
  • Guerin-Stern syndrome
More Names
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What are the signs and symptoms of arthrogryposis multiplex congenita?

The signs and symptoms associated with arthrogryposis multiplex congenita (AMC) can vary greatly in range and severity among affected individuals.[1] The condition is always present at birth (congenital) but does not get worse over time (it is not progressive). In some cases, few joints maybe affected and the range of motion may be nearly normal. In most cases the hands, wrists, elbows, shoulders, hips, feet, and knees are affected. In the most severe cases, nearly every joint in the body may be involved, including those of the jaw and back. The joint contractures are often accompanied by muscle weakness, which may further limit movement.[2]

Last updated: 6/12/2012

  1. Arthrogryposis Multiplex Congenita. NORD. June 21, 2010; Accessed 6/12/2012.
  2. Arthrogryposis: What it is and how it is treated. A National Support Group for Arthrogryposis Multiplex Congenita (AVENUES). Accessed 10/15/2013.