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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Congenital sucrase-isomaltase deficiency


Other Names for this Disease
  • Congenital sucrose-isomaltase malabsorption
  • CSID
  • Disaccharide intolerance, 1
  • SI deficiency
  • Sucrase-isomaltase deficiency, congenital
More Names
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Treatment


Newline Maker

How might congenital sucrase-isomaltase deficiency (CSID) be treated?

CSID is typically treated by modifying a person's diet to reduce the amount of sucrose. Because many foods contain sucrose and other complex sugars, it can be difficult to completely remove sucrase from the diet. Sucraid is an oral medication containing the enzyme that does not work properly in people with this condition. By taking this medication, those with CSID can eat sucrose-containing foods because this enzyme will break down sucrose. This medication must be taken with each meal or snack.[1] 
Last updated: 7/5/2013

References
  1. Congenital sucrase-isomaltase deficiency . Madisons Foundation. September 2007; http://www.madisonsfoundation.org/index.php?option=com_mpower&task=disease&diseaseID=663. Accessed 7/5/2013.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Congenital sucrase-isomaltase deficiency. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.

Medical Products

The medication(s) listed in the table(s) below have been approved by the Food and Drug Administration (FDA) for treatment of this condition. The FDA Office of Orphan Products Development designates "orphan products" for those that treat rare diseases affecting fewer than 200,000 Americans. The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products. To search for all FDA approved drugs, visit Drugs@FDA. You can find orphan products used to treat other conditions by searching the Orphan Drug Product Designation database.


Generic Name Sacrosidase
Trade Name
(Manufacturer Name)
Sucraid®
(QOL Medical, LLC)
Indication
The FDA has approved this product to be used in this manner.
Oral replacement therapy of the genetically determined sucrase deficiency, which is part of congenital sucrease-isomaltase deficiency.
More Information about this product Drug Information Portal