Other Names for this Disease
- Postpartum hypopituitarism
- Postpartum panhypopituitarism
- Postpartum panhypopituitary syndrome
- Postpartum pituitary necrosis
- Simmond's disease
Your QuestionI am curious to know if there is a genetic link to Sheehan syndrome. My maternal grandmother hemorrhaged after her 5th child and ended up losing all of the hair on her body, less the hair on her head. My maternal aunt also hemorrhaged after her 4th child and she too lost all body hair less the hair on her head. Neither were diagnosed with Sheehan syndrome at that time.
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
- enlargement of the pituitary gland;
- a small sella size (the sella is a saddle-shaped depression where the pituitary gland lies);
- disseminated intravascular coagulation (DIC);
It has also been proposed that bleeding disorders (many of which are genetic) may play a role in predisposition to bleeding in individuals with Sheehan syndrome. In general, further studies on the causes and risk factors for Sheehan syndrome are needed.
- Alex H. Tessnow and Jean D. Wilson. The Changing Face of Sheehan’s Syndrome. Am J Med Sci. November 2010; 340(5):402-406.
- Fahrettin Kelestimur. Sheehan's syndrome. Pituitary. 2003; 6(4):181-188.
- Gokalp D, Tuzcu A, Bahceci M, Ayyildiz O, Erdemoglu M, Alpagat G. Assessment of bleeding disorders in Sheehan's syndrome: are bleeding disorders the underlying cause of Sheehan's syndrome?. Platelets. 2011; 22(2):92-97. http://www.ncbi.nlm.nih.gov/pubmed/21133650. Accessed 8/29/2011.