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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Sheehan syndrome


Other Names for this Disease
  • Postpartum hypopituitarism
  • Postpartum panhypopituitarism
  • Postpartum panhypopituitary syndrome
  • Postpartum pituitary necrosis
  • Simmond's disease
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Cause


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What causes Sheehan syndrome?

Sheehan syndrome is caused by severe blood loss during or after childbirth.[1][2][3] Blood loss at that time can be particularly damaging to the pituitary gland (which enlarges during pregnancy), destroying hormone-producing tissue so that the gland cannot function properly.[1][3]  
Last updated: 8/25/2011

References
  1. Schrager S, Sabo L. J Am Board Fam Med. 2001; http://www.jabfm.org/cgi/reprint/14/5/389.pdf. Accessed 2/23/2010.
  2. Vorvick L, Storck S. Sheehan syndrome. MedlinePlus. 2008; http://www.nlm.nih.gov/medlineplus/ency/article/001175.htm. Accessed 2/23/2010.
  3. Sheehan's syndrome. MayoClinic.com. 2009; http://www.mayoclinic.com/print/sheehans-syndrome/DS00889/DSECTION=all&METHOD=print. Accessed 2/23/2010.