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Genetic and Rare Diseases Information Center (GARD)

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Pemphigus


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Overview

Pemphigus is a group of rare autoimmune diseases that cause blistering of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals).[1] This condition can occur at any age, but often strikes people in middle or older age. It is more common in people of Middle Eastern or Jewish descent than in other races and cultures. Pemphigus is a chronic disease which is best controlled by early diagnosis and treatment.[2] Treatment includes steroids to reduce inflammation, drugs that suppress the immune system response and antibiotics to treat associated infections.[3]

There are three main types of pemphigus:[2]

  • Pemphigus vulgaris
  • Pemphigus foliaceus 
  • Paraneoplastic pemphigus
  • Last updated: 3/3/2010

    References

    1. Pemphigus. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). 2007; http://www.niams.nih.gov/Health_Info/Pemphigus/default.asp. Accessed 3/3/2010.
    2. Pemphigus. MayoClinic.com. 2008; http://www.mayoclinic.com/print/pemphigus/DS00749/METHOD=print&DSECTION=all. Accessed 3/3/2010.
    3. Pemphigus. MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/pemphigus.html. Accessed 3/3/2010.
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    Basic Information

    • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
    • The National Institute of Allergy and Infectious Diseases (NIAID) supports scientists developing better ways to diagnose, treat, and prevent the many infectious, immunologic, and allergic diseases that afflict people worldwide. Click on the link to view information on this topic. 
    • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
    • MayoClinic.com provides information about pemphigus. Click on the above link to access this information.

    In Depth Information

    • PubMed is a searchable database of medical literature and lists journal articles that discuss Pemphigus. Click on the link to view a sample search on this topic.
    See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.