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Genetic and Rare Diseases Information Center (GARD)

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Olivopontocerebellar atrophy

Other Names for this Disease
  • OPCA
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Your Question

Would a person in their 80s with this disease become resistive and combative due to the disease itself or would there have to be other causes for this behavior?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

Is olivopontocerebellar atrophy associated with behavior changes in affected adults?

Yes. Olivopontocerebellar atrophy (OPCA) is associated with dementia, cognitive deficits, and emotional disturbances in some patients. In particular, studies have shown people with OPCA to have an increased rate of depression, anxiety, and bodily complaints.[1] These symptoms are also present in some people with multiple system atrophy (MSA). While many people with OPCA do progress to MSA, these symptoms alone are not a predictor for disease progression.
Last updated: 8/29/2013