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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Muenke Syndrome


Other Names for this Disease

  • Muenke nonsyndromic coronal craniosynostosis
  • Syndrome of coronal craniosynostosis
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Cause

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What causes Muenke syndrome?

Muenke syndrome is caused by mutations in the FGFR3 gene. This gene provides instructions for making a protein that is involved in the development and maintenance of bone and brain tissue. A single mutation in the FGFR3 gene causes the FGFR3 protein to be overly active, which interferes with normal bone growth and allows the bones of the skull to fuse before they should.[1]
Last updated: 10/3/2011

References
  1. Muenke syndrome. Genetics Home Reference (GHR). June 2006; http://ghr.nlm.nih.gov/condition/muenke-syndrome. Accessed 10/3/2011.


Other Names for this Disease
  • Muenke nonsyndromic coronal craniosynostosis
  • Syndrome of coronal craniosynostosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.