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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Muenke Syndrome


Other Names for this Disease

  • Muenke nonsyndromic coronal craniosynostosis
  • Syndrome of coronal craniosynostosis
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Overview

Muenke syndrome is a condition characterized by the premature closure of the coronal suture of the skull (coronal craniosynostosis) during development. This affects the shape of the head and face.[1][2] Other variable features include abnormalities of the hands or feet, hearing loss and developmental delay. Muenke syndrome is caused by mutations in the FGFR3 gene. It is inherited in an autosomal dominant pattern.[1]  
Last updated: 10/3/2011

References

  1. Muenke syndrome. Genetics Home Reference (GHR). June 2006; http://ghr.nlm.nih.gov/condition/muenke-syndrome. Accessed 10/3/2011.
  2. Muenke syndrome. Orphanet. January 2006; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=53271. Accessed 10/3/2011.
Your Questions Answered
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Please contact us with your questions about Muenke Syndrome. We will answer your question and update these pages with new resources and information.

Basic Information

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Muenke Syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Muenke nonsyndromic coronal craniosynostosis
  • Syndrome of coronal craniosynostosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.