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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Marfan syndrome


Other Names for this Disease

  • Contractural arachnodactyly
  • Marfan syndrome type 1
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Inheritance

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How is Marfan syndrome inherited?

Marfan syndrome is inherited in an autosomal dominant manner. All individuals inherit 2 copies of each gene. In autosomal dominant conditions, an individual only has to have 1 mutation in the gene to develop the condition. The mutation can be inherited from a parent, or can happen by chance for the first time in an individual.[1]

Each child of an individual with Marfan syndrome has a 50% chance of inheriting the mutation and the disorder. Offspring who inherit the mutation will have Marfan syndrome, although they could be more or less severely affected than their parent.[1]

Last updated: 2/25/2011

References
  1. Harry C. Dietz, MD. Marfan syndrome. GeneReviews. 2011; http://www.ncbi.nlm.nih.gov/books/NBK1335/. Accessed 10/15/2013.


Other Names for this Disease
  • Contractural arachnodactyly
  • Marfan syndrome type 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.