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Mantle cell lymphoma

Other Names for this Disease
  • Lymphoma, mantle cell
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Mantle cell lymphoma (MCL) belongs to a group of diseases known as  non-Hodgkin’s lymphomas (NHL), which are cancers that affect the the lymphatic system (part of the immune system). MCL accounts for 6% of all non-Hodgkin lymphomas and is mostly found in males during their early 60s. [1][2][3] Lymphocytes, which are white blood cells that make up the lymphatic system. There are two main types: B-lymphocytes (B-cells) and T-lymphocytes (T-cells). Mantel cell lymphoma is a B-cell lymphoma that develops from cancerous B-cells within a region of the lymph node known as the mantle zone.[4] Although mantle cell lymphomas are slow-growing cancers, at the time of diagnosis, they are usually widespread in the lymph nodes and require intensive treatment because they can become lethal within a short period of time.[2][3]
Last updated: 7/20/2011


  1. Mantle Cell Lymphomas. Lymphomation. June 2011; Accessed 7/11/2011.
  2. O’Connor OA and Vose JM. Mantle Cell Lymphoma: Getting the Facts. Lymphoma Research Foundation.. Accessed 7/11/2011.
  3. Non Hodgkin Lymphoma. American Cancer Society. October 2010; Accessed 7/11/2011.
  4. Mantle Cell Lymphoma. National Organization for Rare Disorders (NORD). February 2011; Accessed 7/11/2011.
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Basic Information

  • The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.  Click on the link to view information on this topic. 
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Mantle cell lymphoma. Click on the link to view a sample search on this topic.

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