Other Names for this Disease
- Anesthesia related hyperthermia
- Fulminating hyperpyrexia
- Hyperpyrexia malignant
- Malignant hyperpyrexia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
autosomal dominant manner. People with certain inherited muscle diseases (e.g., central core disease and multiminicore disease) also have MH susceptibility.Malignant hyperthermia (MH) is a severe reaction to certain gases used during anesthesia and/or a muscle relaxant used to temporarily paralyze a person during surgery. Signs and symptoms of MH include marked hyperthermia, a rapid heart rate, rapid breathing, acidosis, muscle rigidity, and breakdown of muscle tissue (rhabdomyolysis). Without prompt treatment, MH can be life-threatening. People who are at increased risk for this reaction are said to have MH susceptibility. Susceptibility to MH may be caused by mutations in any of several genes and is inherited in an
Last updated: 6/30/2014
- Malignant Hyperthermia. Genetics Home Reference. 2007; http://ghr.nlm.nih.gov/condition/malignant-hyperthermia. Accessed 4/4/2011.
- Mark Davis, Danielle James, Neil Pollock, Henry Rosenberg, Kathryn Stowell. Malignant hyperthermia. Orphanet. April, 2007; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=423. Accessed 6/30/2014.
- Genetics Home Reference (GHR) contains information on Malignant hyperthermia. This website is maintained by the National Library of Medicine.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Malignant hyperthermia. Click on the link to view a sample search on this topic.