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Genetic and Rare Diseases Information Center (GARD)

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Madelung disease

Other Names for this Disease
  • Benign symmetrical lipomatosis
  • Familial symmetric lipomatosis
  • Launois-Bensaude syndrome
  • Madelung's disease
  • Multiple symmetric lipomatosis
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What are the signs and symptoms of Madelung disease?

The signs and symptoms of Madelung disease vary from person to person. The deposits present in the disease typically occur around the face, the back of the head, the neck, the upper arms, the abdomen, and the back and upper parts of the leg.[1] The most common complaint is the signficant cosmetic deformities associated with the lipomas. However, some patients also complain of movement limitation and neurological disturbances such as difficulty swallowing, hoarseness, sleep problems, tachycardia (rapid heart rate), fluctuation in blood pressure, and breathing issues.[2]
Last updated: 8/18/2011

  1. Madelung's Disease. Cushing's Help and Support. January 26, 2008; Accessed 8/18/2010.
  2. Alameda YA, Torres L, Perez-Mitchell C, Riera A. Madelung disease: A clinical diagnosis. Otolaryngology-Head and Neck Surgery. 2009;
  3. Ramos S, Pinheiro S, Diogo C, Cabral L, Cruzeiro C. Madelung Disease. Annals of Plastic Surgery. 2009;