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Genetic and Rare Diseases Information Center (GARD)

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Limb-girdle muscular dystrophy

Other Names for this Disease
  • LGMD- autosomal recessive
  • Limb girdle muscular dystrophy
  • Limb-girdle muscular dystrophy autosomal recessive
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How is limb-girdle muscular dystrophy inherited?

Limb-girdle muscular dystrophy (LGMD) is most often inherited in an autosomal recessive manner; less commonly, rare sub-types may be inherited in an autosomal dominant manner.  There may be difficulties diagnosing the condition accurately, and often the mode of inheritance cannot be determined. Therefore, it may be challenging to determine the exact recurrence risks for some families.

Establishing the type of LGMD in an affected individual can be useful for discussing the clinical course of the disease as well as for determining who else in the family may be at risk for the condition.[1]
Last updated: 2/23/2012

  1. Erynn Gordon, Elena Pegoraro, Eric P Hoffman. Limb-Girdle Muscular Dystrophy Overview. GeneReviews. July 23, 2009; Accessed 2/20/2012.