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Lemierre syndrome

Other Names for this Disease
  • Necrobacillosis
  • Oropharyngeal infection leading to secondary septic thrombophlebitis of the internal jugular vein
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Lemierre syndrome is a rare disease that is typically characterized by the following four findings: (1) pharyngitis or tonsillitis; followed by (2) oropharyngeal infection with Fusobacterium necrophorum, a bacteria that is normally present in the pharynx, gastrointestinal tract, and genital tract of humans; leading to (3) internal jugular vein thrombosis; and subsequent (4) septic emboli (pus-containing tissue that migrates from its original location in the body to the lungs or other parts of the body). Antibiotics are usually the primary treatment.[1]
Last updated: 11/12/2008


  1. Schwartz RH. Chapter 30: Infections Related to the Upper and Middle Airways. In: Long SS, Pickering LK, Prober CG. Long: Principles and Practice of Pediatric Infectious Diseases, 3rd ed. PA: Churchill Livingstone, An Imprint of Elsevier; 2008;
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In Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Lemierre syndrome. Click on the link to view a sample search on this topic.