Hypoplastic left heart syndrome
Other Names for this Disease
At first, a newborn with HLHS may appear normal. Symptoms usually occur in the first few hours of life, although it may take up to a few days to develop symptoms. These symptoms may include:
- Bluish (cyanosis) or poor skin color
- Cold hands and feet (extremities)
- Poor pulse
- Poor suckling and feeding
- Pounding heart
- Rapid breathing
- Shortness of breath
In healthy newborns, bluish color in the hands and feet is a response to cold (this reaction is called peripheral cyanosis). However, a bluish color in the chest or abdomen, lips, and tongue is abnormal (called central cyanosis). It is a sign that there is not enough oxygen in the blood. Central cyanosis often increases with crying.
The Human Phenotype Ontology provides the following list of signs and symptoms for Hypoplastic left heart syndrome. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms.
The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature.
The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined.
Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
- Facts about Hypoplastic Left Heart Syndrome. Centers for Disease Control and Prevention. April 2011; http://www.cdc.gov/ncbddd/heartdefects/hlhs.html. Accessed 7/21/2011.
- Schumacher KR. Hypoplastic left heart syndrome. MedlinePlus. December 2009; http://www.nlm.nih.gov/medlineplus/ency/article/001106.htm. Accessed 7/21/2011.