Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Transient acantholytic dermatosis

Other Names for this Disease
  • Grover disease
  • Grover's disease
  • TAD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


What is transient acantholytic dermatosis?

How might transient acantholytic dermatosis be treated?

What is transient acantholytic dermatosis?

Transient acantholytic dermatosis, also called Grover disease, is a skin condition that causes the appearance of small, red spots. These spots usually develop on the chest or back, but may also form on other parts of the body. This condition frequently leads to intense itching, although it may cause no symptoms. Most cases last six to twelve months. Occasionally, this condition may persist for longer periods, or it may come and go over time. The exact cause is unknown.[1] 
Last updated: 12/1/2011

How might transient acantholytic dermatosis be treated?

There is no cure for transient acantholytic dermatosis and treatment is usually based on a person's symptoms. Affected individuals are usually advised to avoid strenuous exercise and excessive sun exposure, as sweating may induce more itchy spots. Initial treatment options include topical steroid creams such as hydrocortisone, anti-itch lotions containing menthol or camphor, and calcipotriol cream. For more severe cases, options include tetracycline, isotretinoin, antifungal pills such as itraconazole, PUVA phototherapy, and cortisone injections. These treatments have important side effects and are not necessary for mild cases.[1][2]
Last updated: 12/1/2011

  1. Grover's Disease. New Zealand Dermatological Society. November 2011; Accessed 12/1/2011.
  2. Grover's Disease. American Osteopathic College of Dermatology. 2011; Accessed 12/1/2011.