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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Friedreich ataxia


Other Names for this Disease

  • FRDA
  • Friedreich's ataxia
  • Hereditary spinal ataxia
  • Hereditary spinal sclerosis
  • Spinocerebellar ataxia, Friedreich
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Inheritance

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How is Friedreich ataxia inherited?

Friedreich ataxia is inherited in an autosomal recessive pattern, which means that both copies of the FXN gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene (and are referred to as carriers); but they typically do not show signs and symptoms of the condition. When two people who are carriers of an autosomal recessive condition have a child, each time there is a 25% (1 in 4) chance that the child will have the condition, a 50% (1 in 2) chance that the child will be a carrier like each of the parents, and a 25% (1 in 4) chance that the child will not have the condition and not be a carrier.[1]
Last updated: 1/23/2012

References
  1. Friedreich ataxia. Genetics Home Reference. May 2010; http://ghr.nlm.nih.gov/condition/friedreich-ataxia. Accessed 1/23/2012.


Other Names for this Disease
  • FRDA
  • Friedreich's ataxia
  • Hereditary spinal ataxia
  • Hereditary spinal sclerosis
  • Spinocerebellar ataxia, Friedreich
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.