Fibrodysplasia ossificans progressiva
Other Names for this Disease
- Myositis ossificans
- Myositis ossificans progressiva
- Progressive myositis ossificans
- Progressive ossifying myositis
Your QuestionI have fibrodysplasia ossificans progressiva and recently had my first fracture. I am currently taking medication but continue to have pain in my leg, hand, and elbow. What are the risks of operation? Can myositis ossificans be passed to the next generation?
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Trauma to the muscles of an individual with FOP, such as a fall or invasive medical procedure, or a viral illness may trigger episodes of muscle swelling and inflammation (myositis) followed by more rapid bone growth in the injured area.FOP can be caused by mutations in the ACVR1 gene and is inherited in an autosomal dominant manner.
- Fibrodysplasia ossificans progressiva. Genetic Home Reference. August 2007; http://ghr.nlm.nih.gov/condition/fibrodysplasia-ossificans-progressiva. Accessed 3/16/2011.
- Pignolo R, Kaplan F. Pediatric Fibrodysplasia Ossificans Progressiva. E-medicine. July 30, 2009; http://emedicine.medscape.com/article/1007104-overview. Accessed 3/17/2011.