Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Familial adenomatous polyposis


Other Names for this Disease

  • Adenomatous polyposis coli
  • Adenomatous polyposis of the colon
  • Familial adenomatous polyposis of the colon
  • Familial intestinal polyposis
  • Familial multiple polyposis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Familial adenomatous polyposis (FAP) is an inherited colorectal cancer syndrome. Cancer usually develops in the lower part of the digestive system, including the large intestine (colon) and rectum. People with the classic type of familial adenomatous polyposis may begin to develop multiple noncancerous (benign) polyps (growths) in the colon as early as their teenage years. The average age at which an individual develops colon cancer in classic familial adenomatous polyposis is about 39 years. Mutations in the APC gene cause classic familial adenomatous polyposis.[1]

Last updated: 4/6/2010

References

  1. Familial adenomatous polyposis. Genetics Home Reference Web site. April 2008; http://ghr.nlm.nih.gov/condition=familialadenomatouspolyposis. Accessed 4/6/2010.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

6 question(s) from the public on Familial adenomatous polyposis have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • Genetics Home Reference (GHR) contains information on Familial adenomatous polyposis. This website is maintained by the National Library of Medicine.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.  Click on the link to view information on this topic. 
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Familial adenomatous polyposis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Adenomatous polyposis coli
  • Adenomatous polyposis of the colon
  • Familial adenomatous polyposis of the colon
  • Familial intestinal polyposis
  • Familial multiple polyposis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.