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Genetic and Rare Diseases Information Center (GARD)

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Encephalitis lethargica


Other Names for this Disease

  • Von Economo’s disease
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Overview

Encephalitis lethargica is a disease characterized by high fever, headache, double vision, delayed physical and mental response, extreme tiredness (lethargy), and sometimes coma. Patients may also experience abnormal eye movements, upper body weakness, muscule pain, tremors, neck rigidity, and behavioral changes including psychosis. A world-wide epidemic of encephalitis lethargica occurred from 1917 to 1928. The cause of this condition is unknown, and treatment depends on a person's symptoms. Levodopa and other antiparkinson drugs often produce dramatic responses.[1]
Last updated: 10/14/2008

References

  1. NINDS Encephalitis Lethargica Information Page. National Institute of Neurological Disorders and Stroke Website. February 12, 2007 ; http://www.ninds.nih.gov/disorders/encephalitis_lethargica/encephalitis_lethargica.htm. Accessed 10/14/2008.
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Basic Information

In Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Encephalitis lethargica. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Von Economo’s disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.