Other Names for this Disease
- Atrophic papulosis, malignant
- Degos syndrome
- Degos's malignant atrophic papulosis
- Kohlmeier-Degos disease
- Malignant atrophic papulosis
What are the signs and symptoms of Degos disease?
What causes Degos disease?
How might Degos disease be treated?
What is the typical prognosis (long term outlook) for people with Degos disease?
Skin macules tend to be the earliest symptom in multisystem disease. Small bowel involvement is very common, and Degos disease can cause intestinal perforation (tear). Intestinal perforation is a medical emergency which requires prompt treatment. Click here to learn more about the signs and symptoms of intestinal perforation. Unfortunately intestinal disease tends to recur in these individuals.Degos disease can also affect the nervous system, in particular the cerebral and peripheral nerves. This may result in a variety of symptoms, such as partial paralysis, aphasia (difficulty communicating), cranial neuropathies (which affect nerves that are connected with the brain and control sight, eye movement, hearing, and taste), sensory disturbances, and seizures.
For further information on your treatment options, we encourage you to discuss your questions and this information with your healthcare provider.
- Malignant Atrophic Papulosis. MeSH. http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?mode=&index=24677&view=expanded. Accessed 3/31/2011.
- Mark LA, Mirowski GW. Oral Disease and Oral-Cutaneous Manifestations of Gastrointestinal and Liver Disease. In: Feldman eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease, 9th ed. Philadelphia, PA: Saunders; 2010;
- Cheng TS. A man with generalized small white skin lesions and abdominal pain. Int J Dermatol. 2011 Jun;50(6):726-9; http://www.ncbi.nlm.nih.gov/pubmed/21595670. Accessed 10/26/2011.
- Wilson J . Benign cutaneous Degos disease in a 16-year-old girl. Pediatr Dermatol. 01-JAN-2007;