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Genetic and Rare Diseases Information Center (GARD)

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Cramp-fasciculation syndrome

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What causes cramp-fasciculation syndrome?

Though the exact cause of cramp-fasciculation syndrome is unknown, one article in the medical literature suggests that this condition occurs because of nerve damage acquired over time.  The authors of this article also suggest that cramp-fasciculation syndrome may be a type of autoimmune disease.[1]
Last updated: 6/12/2013

  1. Hart IK, Maddison P, Newsom-Davis J, Vincent A, Mills KR. Phenotypic variants of autoimmune peripheral nerve hyperexcitability. Brain. 2002; 125:1887-1895. Accessed 1/22/2013.