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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Cold agglutinin disease


Other Names for this Disease

  • Anemia, hemolytic, cold antibody
  • CAD
  • Cold antibody disease
  • Cold antibody hemolytic anemia
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Inheritance

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Is cold agglutinin disease inherited?

Cold agglutinin disease (CAD) is not an inherited condition and does not run in families. It is designated as either idiopathic or primary (not associated with an underlying condition), or secondary (associated with or caused by another condition). In some cases CAD may be multifactorial, which means that multiple environmental factors and multiple genes may interact to predispose a person to developing CAD.[1] However, to our knowledge, no disease-causing genes have been identified and no familial cases have been reported.
Last updated: 5/15/2014

References
  1. Marc Michel. Cold agglutinin disease. Orphanet. August, 2010; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=56425. Accessed 5/15/2014.


Other Names for this Disease
  • Anemia, hemolytic, cold antibody
  • CAD
  • Cold antibody disease
  • Cold antibody hemolytic anemia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.