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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Charcot-Marie-Tooth disease


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Other Names for this Disease
  • Charcot Marie Tooth disease
  • CMT
  • Hereditary motor and sensory neuropathy
  • HMSN
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Your Question

What kind of vision loss is associated with Charcot-Marie-Tooth disease?

Our Answer

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What is Charcot-Marie-Tooth disease?

Charcot-Marie-Tooth disease is a group of disorders that affect the peripheral nerves, the nerves running from outside the brain and spine.[1] Defects in at least 30 genes cause different forms of this disease. Common symptoms may include foot drop, foot deformity, loss of lower leg muscle, numbness in the foot or leg, “slapping" gait (feet hit the floor hard when walking), and weakness of the hips, legs, or feet.[1] There is currently no cure for Charcot-Marie-Tooth disease, but physical therapy, occupational therapy, braces and other orthopedic devices, pain medication, and orthopedic surgery can help manage and improve symptoms.[2]

There are over 40 types of Charcot-Marie-Tooth disease. You can search for more information on a particular type of Charcot-Marie-Tooth disease from the GARD Home page. Enter the name of the condition in the GARD search box, and then select the type from the drop down menu.
Last updated: 7/23/2010

What kind of vision loss is associated with Charcot-Marie-Tooth disease?

While vision loss is not commonly associated with most types of Charcot-Marie-Tooth disease [3], it can be found in two forms of the condition.[4][5] X-linked Recessive Charcot-Marie-Tooth disease 5 may be accompanied by progressive loss of vision beginning with optic nerve atrophy prior to age 20.[4] Charcot-Marie-Tooth disease type 4B2 may be accompanied by open-angle glaucoma that can begin in early childhood.[5]
Last updated: 10/6/2011

References