Your QuestionMy mom has had cerebellar degeneration for several years, yet I still know very little about it. Can you provide me with some information?
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- acute and hemorrhagic stroke, when there is lack of blood flow or oxygen to the cerebellum
- cerebellar cortical atrophy, multisystem atrophy and olivopontocerebellar degeneration, progressive degenerative disorders in which cerebellar degeneration is a key feature
- Friedreich’s ataxia, and other spinocerebellar ataxias, which are caused by inherited genetic mutations that progressively kill neurons in the cerebellum, brain stem, and spinal cord
- transmissible spongiform encephalopathies (such as 'Mad Cow Disease' and Creutzfeldt-Jakob disease) in which abnormal proteins cause inflammation in the brain, particularly in the cerebellum
- multiple sclerosis, in which damage to the insulating membrane (myelin) that wraps around and protects nerve cells can involve the cerebellum
Other diseases that can cause cerebellar degeneration include:
Studies have shown that many patients with movement disorders caused by damage to the cerebellum also have psychiatric symptoms. These studies suggest that patients with cerebellar diseases may benefit from screening and treatment of psychiatric symptoms.
- NINDS Cerebellar Degeneration Information Page. National Institute of Neurological Disorders and Stroke (NINDS). June 27, 2008; http://www.ninds.nih.gov/disorders/cerebellar_degeneration/cerebellar_degeneration.htm. Accessed 10/2/2008.
- NINDS Ataxias and Cerebellar or Spinocerebellar Degeneration Information Page. National Institute of Neurological Disorders and Stroke (NINDS). June 3, 2008; http://www.ninds.nih.gov/disorders/ataxia/ataxia.htm. Accessed 10/2/2008.
- Study Finds Psychiatric Disorders are Common in People with Cerebellar Degeneration. National Institute of Neurological Disorders and Stroke (NINDS). March 8, 2005; http://www.ninds.nih.gov/news_and_events/news_articles/news_article_cerebellar.htm. Accessed 10/2/2008.
- Cerebellar Disorders. The Merck Manuals Online Medical Library. August 2007; http://www.merck.com/mmpe/sec16/ch221/ch221j.html. Accessed 10/2/2008.
- Cerebellar Degeneration, Subacute. NORD. 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Cerebellar%20Degeneration%2C%20Subacute. Accessed 3/28/2011.