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Genetic and Rare Diseases Information Center (GARD)

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Binswanger's disease

Other Names for this Disease
  • Dementia multi-infarct
  • Multi-infarct dementia
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Binswanger's disease, also called subcortical vascular dementia, is a type of dementia caused by widespread, microscopic areas of damage to the deep layers of white matter in the brain.[1] Most patients experience progressive memory loss and deterioration of intellectual abilities (dementia), urinary urgency or incontinence, and an abnormally slow, shuffling, unsteady pattern of walking, usually over a 5-10 year period.[2] While there is no cure, the progression of Binswanger's disease can be slowed with healthy lifestyle choices. Treatment is symptomatic and supportive.[1] 
Last updated: 11/9/2009


  1. NINDS Binswanger's Disease Information Page. National Institute of Neurological Disorders and Stroke (NINDS). 2009; Accessed 11/8/2009.
  2. Elble RJ. Binswanger's Disease. National Organization for Rare Disorders (NORD). 2009; Accessed 11/8/2009.
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