Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Bannayan-Riley-Ruvalcaba syndrome


Other Names for this Disease
  • Bannayan-Zonana syndrome
  • BRRS
  • BZS
  • Macrocephaly multiple lipomas and hemangiomata
  • Macrocephaly pseudopapilledema and multiple hemangiomas
More Names
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Cause


Newline Maker

What causes Bannayan-Riley-Ruvalcaba syndrome?

BRRS is caused by specific mutations in the PTEN gene. The PTEN gene provides instructions for making a protein that is found in almost all tissues in the human body. The protein acts as a tumor suppressor, which means that it plays a role in preventing cells from growing and dividing too rapidly or in an uncontrolled way.[1]
Last updated: 3/18/2013

References
  1. PTEN. Genetics Home Reference. September 2012; http://ghr.nlm.nih.gov/gene/PTEN. Accessed 3/18/2013.